YGR240C

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Systematic name YGR240C
Gene name PFK1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:973734..970771
Primary SGDID S000003472


Description of YGR240C: Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes[1][2][3][4][5][6][7]




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References

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  1. Arvanitidis A and Heinisch JJ (1994) Studies on the function of yeast phosphofructokinase subunits by in vitro mutagenesis. J Biol Chem 269(12):8911-8 SGD PMID 8132627
  2. Foy JJ and Bhattacharjee JK (1978) Biosynthesis and regulation of fructose-1,6-bisphosphatase and phosphofructokinase in Saccharomyces cerevisiae grown in the presence of glucose and gluconeogenic carbon sources. J Bacteriol 136(2):647-56 SGD PMID 213420
  3. Kriegel T, et al. (1987) Hydrodynamic studies on the quaternary structure of reacting yeast phosphofructokinase. Biomed Biochim Acta 46(5):349-55 SGD PMID 2959282
  4. Lobo Z and Maitra PK (1983) Phosphofructokinase mutants of yeast. Biochemistry and genetics. J Biol Chem 258(3):1444-9 SGD PMID 6218165
  5. Newcomb LL, et al. (2003) Glucose regulation of Saccharomyces cerevisiae cell cycle genes. Eukaryot Cell 2(1):143-9 SGD PMID 12582131
  6. Nissler K, et al. (1985) An electron microscopy study of the quarternary structure of yeast phosphofructokinase. Biomed Biochim Acta 44(2):251-9 SGD PMID 2408613
  7. Otto A, et al. (1986) Kinetic effects of fructose-1,6-bisphosphate on yeast phosphofructokinase. Biomed Biochim Acta 45(7):865-75 SGD PMID 2947575

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