YGR222W
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| Systematic name | YGR222W |
| Gene name | PET54 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:939923..940804 |
| Primary SGDID | S000003454 |
Description of YGR222W: Mitochondrial inner membrane protein; binds to the 5' UTR of the COX3 mRNA to activate its translation together with Pet122p and Pet494p; also binds to the COX1 Group I intron AI5 beta to facilitate exon ligation during splicing[1][2][3][4]
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References
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- Jump up ↑ Costanzo MC, et al. (1989) The PET54 gene of Saccharomyces cerevisiae: characterization of a nuclear gene encoding a mitochondrial translational activator and subcellular localization of its product. Genetics 122(2):297-305 SGD PMID 2548921
- Jump up ↑ Kaspar BJ, et al. (2008) A shared RNA-binding site in the Pet54 protein is required for translational activation and group I intron splicing in yeast mitochondria. Nucleic Acids Res 36(9):2958-68 SGD PMID 18388132
- Jump up ↑ Naithani S, et al. (2003) Interactions among COX1, COX2, and COX3 mRNA-specific translational activator proteins on the inner surface of the mitochondrial inner membrane of Saccharomyces cerevisiae. Mol Biol Cell 14(1):324-33 SGD PMID 12529447
- Jump up ↑ Valencik ML, et al. (1989) Disruption of the yeast nuclear PET54 gene blocks excision of mitochondrial intron aI5 beta from pre-mRNA for cytochrome c oxidase subunit I. EMBO J 8(12):3899-904 SGD PMID 2555177
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