YGR193C

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Systematic name YGR193C
Gene name PDX1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:885741..884509
Primary SGDID S000003425


Description of YGR193C: Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core[1][2][3]




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References

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  1. Behal RH, et al. (1989) Cloning and nucleotide sequence of the gene for protein X from Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 86(22):8732-6 SGD PMID 2682658
  2. Lawson JE, et al. (1991) Disruption and mutagenesis of the Saccharomyces cerevisiae PDX1 gene encoding the protein X component of the pyruvate dehydrogenase complex. Biochemistry 30(11):2834-9 SGD PMID 2007123
  3. Maeng CY, et al. (1994) Expression, purification, and characterization of the dihydrolipoamide dehydrogenase-binding protein of the pyruvate dehydrogenase complex from Saccharomyces cerevisiae. Biochemistry 33(46):13801-7 SGD PMID 7947791

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