YGR178C

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Systematic name YGR178C
Gene name PBP1
Aliases MRS16
Feature type ORF, Verified
Coordinates Chr VII:853215..851047
Primary SGDID S000003410


Description of YGR178C: Component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; similar to human ataxin-2; interacts with Pab1p to regulate mRNA polyadenylation; interacts with Mkt1p to regulate HO translation[1][2][3][4][5]




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References

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  1. Buchan JR, et al. (2008) P bodies promote stress granule assembly in Saccharomyces cerevisiae. J Cell Biol 183(3):441-55 SGD PMID 18981231
  2. Mangus DA, et al. (1998) Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation. Mol Cell Biol 18(12):7383-96 SGD PMID 9819425
  3. Mangus DA, et al. (2004) Identification of factors regulating poly(A) tail synthesis and maturation. Mol Cell Biol 24(10):4196-206 SGD PMID 15121841
  4. Ralser M, et al. (2005) An integrative approach to gain insights into the cellular function of human ataxin-2. J Mol Biol 346(1):203-14 SGD PMID 15663938
  5. Tadauchi T, et al. (2004) Posttranscriptional regulation of HO expression by the Mkt1-Pbp1 complex. Mol Cell Biol 24(9):3670-81 SGD PMID 15082763

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