YGR171C

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Systematic name YGR171C
Gene name MSM1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:842551..840824
Primary SGDID S000003403


Description of YGR171C: Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p[1][2][3]




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References

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  1. Schwob E, et al. (1988) Purification of the yeast mitochondrial methionyl-tRNA synthetase. Common and distinctive features of the cytoplasmic and mitochondrial isoenzymes. Eur J Biochem 178(1):235-42 SGD PMID 3060359
  2. Senger B, et al. (2001) Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions. J Mol Biol 311(1):205-16 SGD PMID 11469869
  3. Tzagoloff A, et al. (1989) Characterization of MSM1, the structural gene for yeast mitochondrial methionyl-tRNA synthetase. Eur J Biochem 179(2):365-71 SGD PMID 2645139

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