YGR129W

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Systematic name YGR129W
Gene name SYF2
Aliases NTC31
Feature type ORF, Verified
Coordinates Chr VII:750400..751047
Primary SGDID S000003361


Description of YGR129W: Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; isy1 syf2 cells have defective spindles activiating cell cycle arrest[1][2][3]




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References

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  1. Ben-Yehuda S, et al. (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17 SGD PMID 11102353
  2. Chen CH, et al. (2002) Functional and physical interactions between components of the Prp19p-associated complex. Nucleic Acids Res 30(4):1029-37 SGD PMID 11842115
  3. Russell CS, et al. (2000) Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae. RNA 6(11):1565-72 SGD PMID 11105756

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