YGR119C

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Systematic name YGR119C
Gene name NUP57
Aliases
Feature type ORF, Verified
Coordinates Chr VII:729671..728046
Primary SGDID S000003351


Description of YGR119C: FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nic96p and two other FG-nucleoproteins (Nsp1p and Nup49p)[1][2][3][4][5][6][7][8][9]




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References

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  1. Bucci M and Wente SR (1998) A novel fluorescence-based genetic strategy identifies mutants of Saccharomyces cerevisiae defective for nuclear pore complex assembly. Mol Biol Cell 9(9):2439-61 SGD PMID 9725905
  2. Fahrenkrog B, et al. (1998) Molecular architecture of the yeast nuclear pore complex: localization of Nsp1p subcomplexes. J Cell Biol 143(3):577-88 SGD PMID 9813081
  3. Frey S and Gorlich D (2009) FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J 28(17):2554-67 SGD PMID 19680227
  4. Grandi P, et al. (1995) Functional interaction of Nic96p with a core nucleoporin complex consisting of Nsp1p, Nup49p and a novel protein Nup57p. EMBO J 14(1):76-87 SGD PMID 7828598
  5. Lutzmann M, et al. (2005) Reconstitution of Nup157 and Nup145N into the Nup84 complex. J Biol Chem 280(18):18442-51 SGD PMID 15741174
  6. Meinema AC, et al. (2011) Long unfolded linkers facilitate membrane protein import through the nuclear pore complex. Science 333(6038):90-3 SGD PMID 21659568
  7. Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 SGD PMID 17418788
  8. Strawn LA, et al. (2004) Minimal nuclear pore complexes define FG repeat domains essential for transport. Nat Cell Biol 6(3):197-206 SGD PMID 15039779
  9. Terry LJ and Wente SR (2007) Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex. J Cell Biol 178(7):1121-32 SGD PMID 17875746

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