YGR110W

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Systematic name YGR110W
Gene name CLD1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:713709..715046
Primary SGDID S000003342


Description of YGR110W: Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58[1][2][3]




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References

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  1. Beranek A, et al. (2009) Identification of a Cardiolipin-specific Phospholipase Encoded by the Gene CLD1 (YGR110W) in Yeast. J Biol Chem 284(17):11572-8 SGD PMID 19244244
  2. Caba E, et al. (2005) Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae. Mutat Res 575(1-2):34-46 SGD PMID 15878181
  3. Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 SGD PMID 18202368

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