YGR100W

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Systematic name YGR100W
Gene name MDR1
Aliases GYP2, MIC1
Feature type ORF, Verified
Coordinates Chr VII:690245..693097
Primary SGDID S000003332


Description of YGR100W: Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function[1][2][3]




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References

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  1. Albert S and Gallwitz D (1999) Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition. J Biol Chem 274(47):33186-9 SGD PMID 10559187
  2. Lafourcade C, et al. (2003) Opposite roles of the F-box protein Rcy1p and the GTPase-activating protein Gyp2p during recycling of internalized proteins in yeast. Genetics 164(2):469-77 SGD PMID 12807768
  3. Sciorra VA, et al. (2005) Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. Mol Biol Cell 16(2):776-93 SGD PMID 15574876

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