YGR075C
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| Systematic name | YGR075C |
| Gene name | PRP38 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:636875..636147 |
| Primary SGDID | S000003307 |
Description of YGR075C: Unique component of the U4/U6.U5 tri-snRNP particle, required for conformational changes which result in the catalytic activation of the spliceosome; dispensible for spliceosome assembly[1][2]
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References
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- ↑ Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31 SGD PMID 10377396
- ↑ Xie J, et al. (1998) Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation. EMBO J 17(10):2938-46 SGD PMID 9582287
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