YGR029W

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Systematic name YGR029W
Gene name ERV1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:543553..544205
Primary SGDID S000003261


Description of YGR029W: Flavin-linked sulfhydryl oxidase of the mitochondrial intermembrane space (IMS), oxidizes Mia40p as part of a disulfide relay system that promotes IMS retention of imported proteins; ortholog of human hepatopoietin (ALR)[1][2][3]




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References

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  1. Lange H, et al. (2001) An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins. EMBO Rep 2(8):715-20 SGD PMID 11493598
  2. Lee J, et al. (2000) Erv1p from Saccharomyces cerevisiae is a FAD-linked sulfhydryl oxidase. FEBS Lett 477(1-2):62-6 SGD PMID 10899311
  3. Mesecke N, et al. (2005) A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121(7):1059-69 SGD PMID 15989955

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