YGL241W
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| Systematic name | YGL241W |
| Gene name | KAP114 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:45445..48459 |
| Primary SGDID | S000003210 |
Description of YGL241W: Karyopherin, responsible for nuclear import of specific proteins; cargoes include Spt15p, Sua7p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear; function is regulated by sumoylation[1][2][3][4]
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References
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- ↑ Hodges JL, et al. (2005) Nuclear import of TFIIB is mediated by Kap114p, a karyopherin with multiple cargo-binding domains. Mol Biol Cell 16(7):3200-10 SGD PMID 15888545
- ↑ Morehouse H, et al. (1999) The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein. Proc Natl Acad Sci U S A 96(22):12542-7 SGD PMID 10535958
- ↑ Mosammaparast N, et al. (2002) A role for nucleosome assembly protein 1 in the nuclear transport of histones H2A and H2B. EMBO J 21(23):6527-38 SGD PMID 12456659
- ↑ Rothenbusch U, et al. (2012) Sumoylation regulates Kap114-mediated nuclear transport.LID - 10.1038/emboj.2012.102 [doi] EMBO J () SGD PMID 22562154
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