YGL236C
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| Systematic name | YGL236C |
| Gene name | MTO1 |
| Aliases | IPS1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:55796..53787 |
| Primary SGDID | S000003205 |
Description of YGL236C: Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants[1][2]
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References
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- Jump up ↑ Colby G, et al. (1998) MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae. J Biol Chem 273(43):27945-52 SGD PMID 9774408
- Jump up ↑ Umeda N, et al. (2005) Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem 280(2):1613-24 SGD PMID 15509579
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