YGL231C

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Systematic name YGL231C
Gene name EMC4
Aliases
Feature type ORF, Verified
Coordinates Chr VII:63620..63048
Primary SGDID S000003200


Description of YGL231C: Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; human ortholog TMEM85 may function in apoptosis[1][2]




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References

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  1. Jump up Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7 SGD PMID 19325107
  2. Jump up Ring G, et al. (2008) Transmembrane protein 85 from both human (TMEM85) and yeast (YGL231c) inhibit hydrogen peroxide mediated cell death in yeast. FEBS Lett 582(17):2637-42 SGD PMID 18586032

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