YGL222C

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Systematic name YGL222C
Gene name EDC1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:81186..80659
Primary SGDID S000003190


Description of YGL222C: RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p; has a role in translation during heat stress[1][2][3]




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References

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  1. Dunckley T, et al. (2001) Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiae. Genetics 157(1):27-37 SGD PMID 11139489
  2. Neef DW and Thiele DJ (2009) Enhancer of decapping proteins 1 and 2 are important for translation during heat stress in Saccharomyces cerevisiae. Mol Microbiol 73(6):1032-42 SGD PMID 19682251
  3. Schwartz D, et al. (2003) The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme. RNA 9(2):239-51 SGD PMID 12554867

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