YGL219C

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Systematic name YGL219C
Gene name MDM34
Aliases MMM2
Feature type ORF, Verified
Coordinates Chr VII:84257..82878
Primary SGDID S000003187


Description of YGL219C: Mitochondrial component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth[1][2][3][4]




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References

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  1. Dimmer KS, et al. (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15 SGD PMID 15631992
  2. Kornmann B, et al. (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325(5939):477-81 SGD PMID 19556461
  3. Ota K, et al. (2008) A proteomic screen reveals the mitochondrial outer membrane protein Mdm34p as an essential target of the F-box protein Mdm30p. Genes Cells 13(10):1075-85 SGD PMID 18775025
  4. Youngman MJ, et al. (2004) Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol 164(5):677-88 SGD PMID 14981098

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