YGL187C

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Systematic name YGL187C
Gene name COX4
Aliases
Feature type ORF, Verified
Coordinates Chr VII:150171..149704
Primary SGDID S000003155


Description of YGL187C: Subunit IV of cytochrome c oxidase, the terminal member of the mitochondrial inner membrane electron transport chain; precursor N-terminal 25 residues are cleaved during mitochondrial import; phosphorylated; spermidine enhances translation[1][2][3]




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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart from the overall increase in mitochondrial protein mass this protein is induced after the diauxic shift. [4] [5]





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References

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  1. Maarse AC, et al. (1984) Subunit IV of yeast cytochrome c oxidase: cloning and nucleotide sequencing of the gene and partial amino acid sequencing of the mature protein. EMBO J 3(12):2831-7 SGD PMID 6098449
  2. Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
  3. Uemura T, et al. (2009) Polyamine modulon in yeast-Stimulation of COX4 synthesis by spermidine at the level of translation. Int J Biochem Cell Biol 41(12):2538-45 SGD PMID 19695341
  4. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  5. submitted by Steffen Ohlmeier on 2004-04-08

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