YGL163C

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Systematic name YGL163C
Gene name RAD54
Aliases XRS1
Feature type ORF, Verified
Coordinates Chr VII:196403..193707
Primary SGDID S000003131


Description of YGL163C: DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family[1][2][3]




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References

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  1. Clever B, et al. (1997) Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins. EMBO J 16(9):2535-44 SGD PMID 9171366
  2. Petukhova G, et al. (1999) Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA double helix conformation. J Biol Chem 274(41):29453-62 SGD PMID 10506208
  3. Symington LS (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev 66(4):630-70, table of contents SGD PMID 12456786

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