YGL137W

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Systematic name YGL137W
Gene name SEC27
Aliases
Feature type ORF, Verified
Coordinates Chr VII:249869..252738
Primary SGDID S000003105


Description of YGL137W: Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP[1][2][3]




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References

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  1. Duden R, et al. (1994) Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic. J Biol Chem 269(39):24486-95 SGD PMID 7929113
  2. Eugster A, et al. (2004) The alpha- and beta'-COP WD40 domains mediate cargo-selective interactions with distinct di-lysine motifs. Mol Biol Cell 15(3):1011-23 SGD PMID 14699056
  3. Letourneur F, et al. (1994) Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum. Cell 79(7):1199-207 SGD PMID 8001155

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