YGL133W
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| Systematic name | YGL133W |
| Gene name | ITC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:257707..261501 |
| Primary SGDID | S000003101 |
Description of YGL133W: Subunit of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1; similar to mammalian Acf1p, the regulatory subunit of the mammalian ATP-utilizing chromatin assembly and modifying factor (ACF) complex[1][2][3][4]
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References
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- Jump up ↑ Brestovitsky A, et al. (2011) The adenovirus E4orf4 protein targets PP2A to the ACF chromatin-remodeling factor and induces cell death through regulation of SNF2h-containing complexes. Nucleic Acids Res () SGD PMID 21546548
- Jump up ↑ Goldmark JP, et al. (2000) The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p. Cell 103(3):423-33 SGD PMID 11081629
- Jump up ↑ Ruiz C, et al. (2003) Cell-type-dependent repression of yeast a-specific genes requires Itc1p, a subunit of the Isw2p-Itc1p chromatin remodelling complex. Microbiology 149(Pt 2):341-51 SGD PMID 12624196
- Jump up ↑ Sugiyama M and Nikawa J (2001) The Saccharomyces cerevisiae Isw2p-Itc1p complex represses INO1 expression and maintains cell morphology. J Bacteriol 183(17):4985-93 SGD PMID 11489850
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