YGL130W

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Systematic name YGL130W
Gene name CEG1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:266145..267524
Primary SGDID S000003098


Description of YGL130W: Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CET1, an RNA 5'-triphosphatase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide[1][2][3][4][5]




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References

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  1. Bougie I, et al. (2004) Thermodynamics of ligand binding by the yeast mRNA-capping enzyme reveals different modes of binding. Biochem J 384(Pt 2):411-20 SGD PMID 15307816
  2. Itoh N, et al. (1984) Messenger RNA guanylyltransferase from Saccharomyces cerevisiae. I. Purification and subunit structure. J Biol Chem 259(22):13923-9 SGD PMID 6389537
  3. Shatkin AJ and Manley JL (2000) The ends of the affair: capping and polyadenylation. Nat Struct Biol 7(10):838-42 SGD PMID 11017188
  4. Shibagaki Y, et al. (1992) mRNA capping enzyme. Isolation and characterization of the gene encoding mRNA guanylytransferase subunit from Saccharomyces cerevisiae. J Biol Chem 267(14):9521-8 SGD PMID 1315757
  5. Takagi T, et al. (2002) Divergent subunit interactions among fungal mRNA 5'-capping machineries. Eukaryot Cell 1(3):448-57 SGD PMID 12455993

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