YGL122C
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Systematic name | YGL122C |
Gene name | NAB2 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:280523..278946 |
Primary SGDID | S000003090 |
Description of YGL122C: Nuclear polyadenylated RNA-binding protein required for nuclear mRNA export and poly(A) tail length control; binds nuclear pore protein Mlp1p; autoregulates mRNA levels; related to human hnRNPs; nuclear localization sequence binds Kap104p[1][2][3][4][5][6][7]
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References
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- ↑ Anderson JT, et al. (1993) NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability. Mol Cell Biol 13(5):2730-41 SGD PMID 8474438
- ↑ Fasken MB, et al. (2008) Functional Significance of the Interaction between the mRNA-binding Protein, Nab2, and the Nuclear Pore-associated Protein, Mlp1, in mRNA Export. J Biol Chem 283(40):27130-43 SGD PMID 18682389
- ↑ Green DM, et al. (2002) Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p. J Biol Chem 277(10):7752-60 SGD PMID 11779864
- ↑ Hector RE, et al. (2002) Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export. EMBO J 21(7):1800-10 SGD PMID 11927564
- ↑ Roth KM, et al. (2005) The nuclear exosome contributes to autogenous control of NAB2 mRNA levels. Mol Cell Biol 25(5):1577-85 SGD PMID 15713618
- ↑ Truant R, et al. (1998) Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein. Mol Cell Biol 18(3):1449-58 SGD PMID 9488461
- ↑ Wilson SM, et al. (1994) Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. J Cell Biol 127(5):1173-84 SGD PMID 7962083
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