YGL106W

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Systematic name YGL106W
Gene name MLC1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:306560..307009
Primary SGDID S000003074


Description of YGL106W: Essential light chain for Myo1p, light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition[1][2][3]




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References

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  1. Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 SGD PMID 15210731
  2. Stevens RC and Davis TN (1998) Mlc1p is a light chain for the unconventional myosin Myo2p in Saccharomyces cerevisiae. J Cell Biol 142(3):711-22 SGD PMID 9700160
  3. Wagner W, et al. (2002) Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p. EMBO J 21(23):6397-408 SGD PMID 12456647

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