YGL105W
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| Systematic name | YGL105W |
| Gene name | ARC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:307437..308567 |
| Primary SGDID | S000003073 |
Description of YGL105W: Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids[1][2][3][4][5]
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References
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- ↑ Deinert K, et al. (2001) Arc1p organizes the yeast aminoacyl-tRNA synthetase complex and stabilizes its interaction with the cognate tRNAs. J Biol Chem 276(8):6000-8 SGD PMID 11069915
- ↑ Frantz JD and Gilbert W (1995) A novel yeast gene product, G4p1, with a specific affinity for quadruplex nucleic acids. J Biol Chem 270(35):20692-7 SGD PMID 7657649
- ↑ Galani K, et al. (2001) The intracellular location of two aminoacyl-tRNA synthetases depends on complex formation with Arc1p. EMBO J 20(23):6889-98 SGD PMID 11726524
- ↑ Simos G, et al. (1996) The yeast protein Arc1p binds to tRNA and functions as a cofactor for the methionyl- and glutamyl-tRNA synthetases. EMBO J 15(19):5437-48 SGD PMID 8895587
- ↑ Simos G, et al. (1998) A conserved domain within Arc1p delivers tRNA to aminoacyl-tRNA synthetases. Mol Cell 1(2):235-42 SGD PMID 9659920
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