YGL090W

From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YGL090W
Gene name LIF1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:343319..344584
Primary SGDID S000003058


Description of YGL090W: Component of the DNA ligase IV complex that mediates nonhomologous end joining in DNA double-strand break repair; physically interacts with Dnl4p and Nej1p; homologous to mammalian XRCC4 protein[1][2][3]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Deshpande RA and Wilson TE (2007) Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4. DNA Repair (Amst) 6(10):1507-16 SGD PMID 17567543
  2. Herrmann G, et al. (1998) Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4. EMBO J 17(14):4188-98 SGD PMID 9670033
  3. Teo SH and Jackson SP (2000) Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks. Curr Biol 10(3):165-8 SGD PMID 10679327

See Help:Categories on how to add the wiki page for this gene to a Category </protect>