YGL058W

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Systematic name YGL058W
Gene name RAD6
Aliases PSO8, UBC2
Feature type ORF, Verified
Coordinates Chr VII:393986..394504
Primary SGDID S000003026


Description of YGL058W: Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (as a heterodimer with Rad18p), DSBR and checkpoint control (as a heterodimer with Bre1p), ubiquitin-mediated N-end rule protein degradation (as a heterodimer with Ubr1p[1][2][3][4]




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References

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  1. Game JC and Chernikova SB (2009) The role of RAD6 in recombinational repair, checkpoints and meiosis via histone modification. DNA Repair (Amst) 8(4):470-82 SGD PMID 19230796
  2. Jentsch S, et al. (1987) The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329(6135):131-4 SGD PMID 3306404
  3. Ulrich HD (2009) Regulating post-translational modifications of the eukaryotic replication clamp PCNA. DNA Repair (Amst) 8(4):461-9 SGD PMID 19217833
  4. Varshavsky A (1996) The N-end rule: functions, mysteries, uses. Proc Natl Acad Sci U S A 93(22):12142-9 SGD PMID 8901547

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