YGL049C
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| Systematic name | YGL049C |
| Gene name | TIF4632 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:409604..406860 |
| Primary SGDID | S000003017 |
Description of YGL049C: Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); TIF4632 has a paralog, TIF4631, that arose from the whole genome duplication[1][2][3][4]
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References
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- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Dominguez D, et al. (1999) Interaction of translation initiation factor eIF4G with eIF4A in the yeast Saccharomyces cerevisiae. J Biol Chem 274(38):26720-6 SGD PMID 10480875
- ↑ Goyer C, et al. (1993) TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function. Mol Cell Biol 13(8):4860-74 SGD PMID 8336723
- ↑ Tarun SZ Jr, et al. (1997) Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation. Proc Natl Acad Sci U S A 94(17):9046-51 SGD PMID 9256432
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