YGL018C

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Systematic name YGL018C
Gene name JAC1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:459664..459110
Primary SGDID S000002986


Description of YGL018C: Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria, involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix[1][2][3]




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References

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  1. Andrew AJ, et al. (2006) Characterization of the interaction between the J-protein Jac1p and the scaffold for Fe-S cluster biogenesis, Isu1p. J Biol Chem 281(21):14580-7 SGD PMID 16551614
  2. Kim R, et al. (2001) J-domain protein, Jac1p, of yeast mitochondria required for iron homeostasis and activity of Fe-S cluster proteins. J Biol Chem 276(20):17524-32 SGD PMID 11278728
  3. Voisine C, et al. (2001) Jac1, a mitochondrial J-type chaperone, is involved in the biogenesis of Fe/S clusters in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 98(4):1483-8 SGD PMID 11171977

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