YFR034C
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| Systematic name | YFR034C |
| Gene name | PHO4 |
| Aliases | phoD |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:225958..225020 |
| Primary SGDID | S000001930 |
Description of YFR034C: Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p,; function is regulated by phosphorylation at multiple sites and by phosphate availability[1][2][3][4]
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References
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- ↑ Berben G, et al. (1990) The yeast regulatory gene PHO4 encodes a helix-loop-helix motif. Yeast 6(5):451-4 SGD PMID 2220078
- ↑ Komeili A and O'Shea EK (1999) Roles of phosphorylation sites in regulating activity of the transcription factor Pho4. Science 284(5416):977-80 SGD PMID 10320381
- ↑ Ogawa N and Oshima Y (1990) Functional domains of a positive regulatory protein, PHO4, for transcriptional control of the phosphatase regulon in Saccharomyces cerevisiae. Mol Cell Biol 10(5):2224-36 SGD PMID 2183025
- ↑ Zhou X and O'Shea EK (2011) Integrated Approaches Reveal Determinants of Genome-wide Binding and Function of the Transcription Factor Pho4. Mol Cell 42(6):826-36 SGD PMID 21700227
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