YER173W
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Systematic name | YER173W |
Gene name | RAD24 |
Aliases | RS1 |
Feature type | ORF, Verified |
Coordinates | Chr V:536300..538279 |
Primary SGDID | S000000975 |
Description of YER173W: Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein[1][2][3]
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References
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- ↑ Lydall D, et al. (1996) A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383(6603):840-3 SGD PMID 8893012
- ↑ Majka J and Burgers PM (2003) Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc Natl Acad Sci U S A 100(5):2249-54 SGD PMID 12604797
- ↑ Shinohara M, et al. (2003) The mitotic DNA damage checkpoint proteins Rad17 and Rad24 are required for repair of double-strand breaks during meiosis in yeast. Genetics 164(3):855-65 SGD PMID 12871899
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