YER120W
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| Systematic name | YER120W |
| Gene name | SCS2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:401135..401869 |
| Primary SGDID | S000000922 |
Description of YER120W: Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog[1][2][3][4]
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References
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- ↑ Craven RJ and Petes TD (2001) The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects. Genetics 158(1):145-54 SGD PMID 11333225
- ↑ Kagiwada S and Zen R (2003) Role of the yeast VAP homolog, Scs2p, in INO1 expression and phospholipid metabolism. J Biochem 133(4):515-22 SGD PMID 12761300
- ↑ Kagiwada S, et al. (1998) The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism. J Bacteriol 180(7):1700-8 SGD PMID 9537365
- ↑ Loewen CJ and Levine TP (2005) A highly conserved binding site in vesicle-associated membrane protein-associated protein (VAP) for the FFAT motif of lipid-binding proteins. J Biol Chem 280(14):14097-104 SGD PMID 15668246
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