YER118C
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| Systematic name | YER118C |
| Gene name | SHO1 |
| Aliases | SSU81 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:399055..397952 |
| Primary SGDID | S000000920 |
Description of YER118C: Transmembrane osmosensor involved in activation of the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway; phosphorylated by Hog1p; interacts with Pbs2p, Msb2p, Hkr1p, and Ste11p[1][2][3][4][5][6][7]
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References
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- ↑ Cullen PJ, et al. (2004) A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast. Genes Dev 18(14):1695-708 SGD PMID 15256499
- ↑ Hao N, et al. (2007) A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway. Curr Biol 17(8):659-67 SGD PMID 17363249
- ↑ O'Rourke SM and Herskowitz I (2004) Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis. Mol Biol Cell 15(2):532-42 SGD PMID 14595107
- ↑ Posas F and Saito H (1997) Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 276(5319):1702-5 SGD PMID 9180081
- ↑ Tatebayashi K, et al. (2006) Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway. EMBO J 25(13):3033-44 SGD PMID 16778768
- ↑ Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33 SGD PMID 17627274
- ↑ Zarrinpar A, et al. (2003) Optimization of specificity in a cellular protein interaction network by negative selection. Nature 426(6967):676-80 SGD PMID 14668868
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