YER111C

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Systematic name YER111C
Gene name SWI4
Aliases ART1
Feature type ORF, Verified
Coordinates Chr V:385876..382595
Primary SGDID S000000913


Description of YER111C: DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair[1][2][3][4][5][6][7]




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References

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  1. Andrews BJ and Herskowitz I (1989) The yeast SWI4 protein contains a motif present in developmental regulators and is part of a complex involved in cell-cycle-dependent transcription. Nature 342(6251):830-3 SGD PMID 2689885
  2. Andrews BJ and Moore LA (1992) Interaction of the yeast Swi4 and Swi6 cell cycle regulatory proteins in vitro. Proc Natl Acad Sci U S A 89(24):11852-6 SGD PMID 1465410
  3. Harrington LA and Andrews BJ (1996) Binding to the yeast SwI4,6-dependent cell cycle box, CACGAAA, is cell cycle regulated in vivo. Nucleic Acids Res 24(4):558-65 SGD PMID 8604294
  4. Nasmyth K and Dirick L (1991) The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast. Cell 66(5):995-1013 SGD PMID 1832338
  5. Ogas J, et al. (1991) Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription. Cell 66(5):1015-26 SGD PMID 1832336
  6. Sidorova J and Breeden L (1993) Analysis of the SWI4/SWI6 protein complex, which directs G1/S-specific transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(2):1069-77 SGD PMID 8423776
  7. Spellman PT, et al. (1998) Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol Biol Cell 9(12):3273-97 SGD PMID 9843569

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