YER075C
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| Systematic name | YER075C |
| Gene name | PTP3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:311199..308413 |
| Primary SGDID | S000000877 |
Description of YER075C: Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm[1][2][3][4]
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References
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- Jump up ↑ Mattison CP and Ota IM (2000) Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast. Genes Dev 14(10):1229-35 SGD PMID 10817757
- Jump up ↑ Mattison CP, et al. (1999) Differential regulation of the cell wall integrity mitogen-activated protein kinase pathway in budding yeast by the protein tyrosine phosphatases Ptp2 and Ptp3. Mol Cell Biol 19(11):7651-60 SGD PMID 10523653
- Jump up ↑ Winkler A, et al. (2002) Heat stress activates the yeast high-osmolarity glycerol mitogen-activated protein kinase pathway, and protein tyrosine phosphatases are essential under heat stress. Eukaryot Cell 1(2):163-73 SGD PMID 12455951
- Jump up ↑ Wurgler-Murphy SM, et al. (1997) Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases. Mol Cell Biol 17(3):1289-97 SGD PMID 9032256
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