YER063W
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Systematic name | YER063W |
Gene name | THO1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr V:281710..282366 |
Primary SGDID | S000000865 |
Description of YER063W: Conserved nuclear RNA-binding protein; specifically binds to transcribed chromatin in a THO- and RNA-dependent manner, genetically interacts with shuttling hnRNP NAB2; overproduction suppresses transcriptional defect caused by hpr1 mutation[1][2]
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References
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- ↑ Jimeno S, et al. (2006) Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants. Mol Cell Biol 26(12):4387-98 SGD PMID 16738307
- ↑ Piruat JI and Aguilera A (1998) A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination. EMBO J 17(16):4859-72 SGD PMID 9707445
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