YER042W
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| Systematic name | YER042W |
| Gene name | MXR1 |
| Aliases | MSRA |
| Feature type | ORF, Verified |
| Coordinates | Chr V:234937..235491 |
| Primary SGDID | S000000844 |
Description of YER042W: Methionine-S-sulfoxide reductase, involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan[1][2][3][4][5][6]
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References
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- ↑ Koc A, et al. (2004) Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging. Proc Natl Acad Sci U S A 101(21):7999-8004 SGD PMID 15141092
- ↑ Kryukov GV, et al. (2002) Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase. Proc Natl Acad Sci U S A 99(7):4245-50 SGD PMID 11929995
- ↑ Le DT, et al. (2009) Functional Analysis of Free Methionine-R-sulfoxide Reductase from Saccharomyces cerevisiae. J Biol Chem 284(7):4354-64 SGD PMID 19049972
- ↑ Moskovitz J, et al. (1997) The yeast peptide-methionine sulfoxide reductase functions as an antioxidant in vivo. Proc Natl Acad Sci U S A 94(18):9585-9 SGD PMID 9275166
- ↑ Moskovitz J, et al. (1998) Overexpression of peptide-methionine sulfoxide reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress. Proc Natl Acad Sci U S A 95(24):14071-5 SGD PMID 9826655
- ↑ Sideri TC, et al. (2009) Methionine sulphoxide reductases protect iron-sulphur clusters from oxidative inactivation in yeast. Microbiology 155(Pt 2):612-23 SGD PMID 19202110
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