YER038C
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Systematic name | YER038C |
Gene name | KRE29 |
Aliases | NSE6 |
Feature type | ORF, Verified |
Coordinates | Chr V:228252..226858 |
Primary SGDID | S000000840 |
Description of YER038C: Subunit of the SMC5-SMC6 complex; this complex is involved in removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance[1][2][3]
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References
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- Jump up ↑ Bermudez-Lopez M, et al. (2010) The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages. Nucleic Acids Res 38(19):6502-12 SGD PMID 20571088
- Jump up ↑ Page N, et al. (2003) A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin. Genetics 163(3):875-94 SGD PMID 12663529
- Jump up ↑ Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82 SGD PMID 15738391
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