YEL063C

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Systematic name YEL063C
Gene name CAN1
Aliases
Feature type ORF, Verified
Coordinates Chr V:33466..31694
Primary SGDID S000000789


Description of YEL063C: Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance[1][2][3][4][5]




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References

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  1. Ahmad M and Bussey H (1986) Yeast arginine permease: nucleotide sequence of the CAN1 gene. Curr Genet 10(8):587-92 SGD PMID 3327612
  2. Broach JR, et al. (1979) Transformation in yeast: development of a hybrid cloning vector and isolation of the CAN1 gene. Gene 8(1):121-33 SGD PMID 395029
  3. Larimer FW, et al. (1978) Mutagenicity of methylated N-nitrosopiperidines in Saccharomyces cerevisiae. Mutat Res 57(2):155-61 SGD PMID 351388
  4. Malinska K, et al. (2003) Visualization of protein compartmentation within the plasma membrane of living yeast cells. Mol Biol Cell 14(11):4427-36 SGD PMID 14551254
  5. Opekarova M, et al. (2002) Phosphatidyl ethanolamine is essential for targeting the arginine transporter Can1p to the plasma membrane of yeast. Biochim Biophys Acta 1564(1):9-13 SGD PMID 12100990

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