YEL059C-A

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Systematic name YEL059C-A
Gene name SOM1
Aliases
Feature type ORF, Verified
Coordinates Chr V:42624..42400
Primary SGDID S000002954


Description of YEL059C-A: Subunit of the mitochondrial inner membrane peptidase, which is required for maturation of mitochondrial proteins of the intermembrane space; Som1p facilitates cleavage of a subset of substrates; contains twin cysteine-x9-cysteine motifs[1][2][3][4][5]




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References

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  1. Bauerfeind M, et al. (1998) The Saccharomyces cerevisiae SOM1 gene: heterologous complementation studies, homologues in other organisms, and association of the gene product with the inner mitochondrial membrane. Mol Gen Genet 257(6):635-40 SGD PMID 9604886
  2. Esser K, et al. (1996) SOM 1, a small new gene required for mitochondrial inner membrane peptidase function in Saccharomyces cerevisiae. Mol Gen Genet 252(4):437-45 SGD PMID 8879245
  3. Jan PS, et al. (2000) Som1, a third component of the yeast mitochondrial inner membrane peptidase complex that contains Imp1 and Imp2. Mol Gen Genet 263(3):483-91 SGD PMID 10821182
  4. Liang H, et al. (2004) Cargo sequences are important for Som1p-dependent signal peptide cleavage in yeast mitochondria. J Biol Chem 279(38):39396-400 SGD PMID 15254042
  5. Longen S, et al. (2009) Systematic analysis of the twin cx(9)c protein family. J Mol Biol 393(2):356-68 SGD PMID 19703468

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