YDR528W

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Systematic name YDR528W
Gene name HLR1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1494586..1495857
Primary SGDID S000002936


Description of YDR528W: Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A;
HLR1 has a paralog, LRE1, that arose from the whole genome duplication[1][2][3]




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References

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  1. Alonso-Monge R, et al. (2001) Hyperosmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects. Mol Microbiol 41(3):717-30 SGD PMID 11532139
  2. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  3. Versele M and Thevelein JM (2001) Lre1 affects chitinase expression, trehalose accumulation and heat resistance through inhibition of the Cbk1 protein kinase in Saccharomyces cerevisiae. Mol Microbiol 41(6):1311-26 SGD PMID 11580836

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