YDR463W

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Systematic name YDR463W
Gene name STP1
Aliases BAP1, SSY2
Feature type ORF, Verified
Coordinates Chr IV:1386816..1388375
Primary SGDID S000002871


Description of YDR463W: Transcription factor, undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing[1][2][3][4][5]




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References

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  1. Andreasson C and Ljungdahl PO (2002) Receptor-mediated endoproteolytic activation of two transcription factors in yeast. Genes Dev 16(24):3158-72 SGD PMID 12502738
  2. Andreasson C, et al. (2006) Regulation of transcription factor latency by receptor-activated proteolysis. Genes Dev 20(12):1563-8 SGD PMID 16778074
  3. Jorgensen MU, et al. (1997) STP1, a gene involved in pre-tRNA processing in yeast, is important for amino-acid uptake and transcription of the permease gene BAP2. Curr Genet 31(3):241-7 SGD PMID 9065387
  4. Wang SS, et al. (1992) STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs. Mol Cell Biol 12(6):2633-43 SGD PMID 1588961
  5. de Boer M, et al. (2000) Stp1p, Stp2p and Abf1p are involved in regulation of expression of the amino acid transporter gene BAP3 of Saccharomyces cerevisiae. Nucleic Acids Res 28(4):974-81 SGD PMID 10648791

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