YDR437W

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Systematic name YDR437W
Gene name GPI19
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1337352..1337774
Primary SGDID S000002845


Description of YDR437W: Subunit of GPI-GlcNAc transferase involved in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), which is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis, shares similarity with mammalian PIG-P[1][2]




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References

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  1. Newman HA, et al. (2005) Gpi19, the Saccharomyces cerevisiae homologue of mammalian PIG-P, is a subunit of the initial enzyme for glycosylphosphatidylinositol anchor biosynthesis. Eukaryot Cell 4(11):1801-7 SGD PMID 16278447
  2. Watanabe R, et al. (2000) Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2. EMBO J 19(16):4402-11 SGD PMID 10944123

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