YDR430C

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Systematic name YDR430C
Gene name CYM1
Aliases MOP112
Feature type ORF, Verified
Coordinates Chr IV:1328470..1325501
Primary SGDID S000002838


Description of YDR430C: Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology[1][2]




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References

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  1. Jonson L, et al. (2004) Enhanced peptide secretion by gene disruption of CYM1, a novel protease in Saccharomyces cerevisiae. Eur J Biochem 271(23-24):4788-97 SGD PMID 15606766
  2. Kambacheld M, et al. (2005) Role of the novel metallopeptidase Mop112 and saccharolysin for the complete degradation of proteins residing in different subcompartments of mitochondria. J Biol Chem 280(20):20132-9 SGD PMID 15772085

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