YDR423C

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Systematic name YDR423C
Gene name CAD1
Aliases YAP2
Feature type ORF, Verified
Coordinates Chr IV:1319275..1318046
Primary SGDID S000002831


Description of YDR423C: AP-1-like basic leucine zipper (bZIP) transcriptional activator involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA[1][2][3][4][5][6][7]




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References

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  1. Cohen BA, et al. (2002) Discrimination between paralogs using microarray analysis: application to the Yap1p and Yap2p transcriptional networks. Mol Biol Cell 13(5):1608-14 SGD PMID 12006656
  2. Fernandes L, et al. (1997) Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol Cell Biol 17(12):6982-93 SGD PMID 9372930
  3. Hirata D, et al. (1994) Stress-induced transcriptional activation mediated by YAP1 and YAP2 genes that encode the Jun family of transcriptional activators in Saccharomyces cerevisiae. Mol Gen Genet 242(3):250-6 SGD PMID 8107671
  4. Lesuisse E and Labbe P (1995) Effects of cadmium and of YAP1 and CAD1/YAP2 genes on iron metabolism in the yeast Saccharomyces cerevisiae. Microbiology 141 ( Pt 11):2937-43 SGD PMID 8535522
  5. Miyahara K, et al. (1996) yAP-1- and yAP-2-mediated, heat shock-induced transcriptional activation of the multidrug resistance ABC transporter genes in Saccharomyces cerevisiae. Curr Genet 29(2):103-5 SGD PMID 8821655
  6. Vilela C, et al. (1998) The yeast transcription factor genes YAP1 and YAP2 are subject to differential control at the levels of both translation and mRNA stability. Nucleic Acids Res 26(5):1150-9 SGD PMID 9469820
  7. Vilela C, et al. (1999) Post-termination ribosome interactions with the 5'UTR modulate yeast mRNA stability. EMBO J 18(11):3139-52 SGD PMID 10357825

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