YDR420W
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Systematic name | YDR420W |
Gene name | HKR1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IV:1306267..1311675 |
Primary SGDID | S000002828 |
Description of YDR420W: Mucin family member that functions as an osmosensor in the Sho1p-mediated HOG pathway with Msb2p; proposed to be a negative regulator of filamentous growth; mutant displays defects in beta-1,3 glucan synthesis and bud site selection[1][2][3]
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References
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- Jump up ↑ Pitoniak A, et al. (2009) The signaling mucins Msb2 and Hkr1 differentially regulate the filamentation mitogen-activated protein kinase pathway and contribute to a multimodal response. Mol Biol Cell 20(13):3101-14 SGD PMID 19439450
- Jump up ↑ Tatebayashi K, et al. (2007) Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 26(15):3521-33 SGD PMID 17627274
- Jump up ↑ Yabe T, et al. (1996) HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae. J Bacteriol 178(2):477-83 SGD PMID 8550469
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