YDR411C

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Systematic name YDR411C
Gene name DFM1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1294394..1293369
Primary SGDID S000002819


Description of YDR411C: Endoplasmic reticulum (ER) localized protein involved in ER-associated protein degradation (ERAD), ER stress and homeostasis; interacts with components of ERAD-L and ERAD-C and Cdc48p; derlin-like family member similar to Der1p[1][2][3]




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References

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  1. Hitt R and Wolf DH (2004) Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins. FEMS Yeast Res 4(7):721-9 SGD PMID 15093775
  2. Sato BK and Hampton RY (2006) Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis. Yeast 23(14-15):1053-64 SGD PMID 17083136
  3. Stolz A, et al. (2010) Dfm1 forms distinct complexes with Cdc48 and the ER ubiquitin ligases and is required for ERAD. Traffic 11(10):1363-9 SGD PMID 20579315

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