YDR406W

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Systematic name YDR406W
Gene name PDR15
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1279210..1283799
Primary SGDID S000002814


Description of YDR406W: Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element[1][2][3][4]




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References

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  1. Decottignies A, et al. (1998) ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p. J Biol Chem 273(20):12612-22 SGD PMID 9575223
  2. Hikkel I, et al. (2003) A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast. J Biol Chem 278(13):11427-32 SGD PMID 12529331
  3. Wolfger H, et al. (1997) The yeast ATP binding cassette (ABC) protein genes PDR10 and PDR15 are novel targets for the Pdr1 and Pdr3 transcriptional regulators. FEBS Lett 418(3):269-74 SGD PMID 9428726
  4. Wolfger H, et al. (2004) The yeast Pdr15p ATP-binding cassette (ABC) protein is a general stress response factor implicated in cellular detoxification. J Biol Chem 279(12):11593-9 SGD PMID 14699125

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