YDR318W
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| Systematic name | YDR318W |
| Gene name | MCM21 |
| Aliases | CTF5 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1103758..1104947 |
| Primary SGDID | S000002726 |
Description of YDR318W: Component of the kinetochore sub-complex COMA; COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) bridges kinetochore subunits in contact with centromeric DNA with subunits bound to microtubules during kinetochore assembly; involved in minichromosome maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-O and fission yeast mal2[1][2][3]
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References
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- Jump up ↑ De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 SGD PMID 14633972
- Jump up ↑ Poddar A, et al. (1999) MCM21 and MCM22, two novel genes of the yeast Saccharomyces cerevisiae are required for chromosome transmission. Mol Microbiol 31(1):349-60 SGD PMID 9987135
- Jump up ↑ Schleiffer A, et al. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol 14(6):604-13 SGD PMID 22561346
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