YDR315C

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Systematic name YDR315C
Gene name IPK1
Aliases GSL1
Feature type ORF, Verified
Coordinates Chr IV:1093586..1092741
Primary SGDID S000002723


Description of YDR315C: Inositol 1,3,4,5,6-pentakisphosphate 2-kinase, nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate (phytate), which is integral to cell function; has 2 motifs conserved in other fungi; ipk1 gle1 double mutant is inviable[1][2]




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References

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  1. Ives EB, et al. (2000) Biochemical and functional characterization of inositol 1,3,4,5, 6-pentakisphosphate 2-kinases. J Biol Chem 275(47):36575-83 SGD PMID 10960485
  2. York JD, et al. (1999) A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science 285(5424):96-100 SGD PMID 10390371

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