YDR301W
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| Systematic name | YDR301W |
| Gene name | CFT1 |
| Aliases | YHH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1063352..1067425 |
| Primary SGDID | S000002709 |
Description of YDR301W: RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF[1][2][3][4][5]
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References
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- ↑ Dichtl B, et al. (2002) Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination. EMBO J 21(15):4125-35 SGD PMID 12145212
- ↑ Ohnacker M, et al. (2000) The WD-repeat protein pfs2p bridges two essential factors within the yeast pre-mRNA 3'-end-processing complex. EMBO J 19(1):37-47 SGD PMID 10619842
- ↑ Preker PJ, et al. (1997) A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16(15):4727-37 SGD PMID 9303317
- ↑ Stumpf G and Domdey H (1996) Dependence of yeast pre-mRNA 3'-end processing on CFT1: a sequence homolog of the mammalian AAUAAA binding factor. Science 274(5292):1517-20 SGD PMID 8929410
- ↑ Zhao J, et al. (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8 SGD PMID 9099738
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